2019年5月号　『 認知機能障害� �リスク薬』.pdf

Certain medications can increase the risk of cognitive impairment, particularly in elderly individuals, those with liver or kidney dysfunction, and those taking multiple medications. Medications that may contribute to cognitive impairment include antipsychotics, anticholinergics, sedatives, and certain antidepressants. The risk of cognitive impairment is higher in individuals with pre-existing conditions such as Alzheimer's disease, Parkinson's disease, or stroke.

Medications that may cause cognitive impairment include:
- Antipsychotics: quetiapine, chlorpromazine, and haloperidol
- Anticholinergics: atropine and scopolamine
- Sedatives: benzodiazepines, such as alprazolam and diazepam
- Antidepressants: amitriptyline, imipramine, and paroxetine
- Antihistamines: diphenhydramine and chlorpheniramine
- Anti-anxiety medications: benzodiazepines and buspirone
- Sleep aids: zolpidem and eszopiclone
- Opioid pain medications: morphine, codeine, and fentanyl
- Steroids: prednisone and dexamethasone
- Anticonvulsants: carbamazepine, phenytoin, and valproate
- Antihypertensives: beta blockers and diuretics

It is essential to weigh the benefits and risks of medications and to monitor patients for signs of cognitive impairment.