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NEL300309A03.pdf
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🔗 Source: nel.edu
📊 Size: 273 KB
📄 Pages: 5 pages
⬇️ Downloads: 53

Summary

Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide, and celecoxib in mice. The study found that guaifenesin, when administered simultaneously with subanalgesic doses of these non-steroidal anti-inflammatory drugs (NSAIDs), resulted in significant antinociceptive effects. Guaifenesin alone did not produce any antinociceptive effect. The plasma levels of nimesulide were significantly higher when administered with guaifenesin compared to nimesulide monotherapy. The results suggest that guaifenesin may enhance the analgesic activity of various NSAIDs.

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Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide, and celecoxib in mice.

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  • File Format: PDF
  • File Size: 273 KB
  • Pages: 5
  • Language: EN
  • Total Downloads: 53
  • Last Updated: 2 weeks ago

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