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Resilience And Immune Function In Older Adults.pdf

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Preview of Resilience and Immune Function in Older Adults
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📊 Size: 146 KB
👤 Author: emacuser
⬇️ Downloads: 187

Summary

Normal aging is marked by dysregulated immune function or immunosenescence, with cell-mediated immunity decreasing and systemic inflammation increasing, making older adults more susceptible to diseases like cancer, heart disease, and infectious diseases. However, there is considerable variation in the degree to which adults are susceptible or resilient to immune dysregulation and disease. Stress is a significant factor that can further alter the aging immune system, and psychological stress can diminish immune responses, slow wound healing, and enhance inflammation. Research on dementia family caregiving has shown that chronic stress can exacerbate age-related declines in immunity, with caregivers having poorer antibody responses to vaccination, poorer control of latent viruses, and higher systemic inflammation. Factors that promote resilience to age-related immune dysregulation are being explored, and evidence suggests that some of the most important factors that augment or assuage an older adult's capacity for resilience develop long before they reach older adulthood.

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Description

Normal aging is marked by dysregulated immune function or immunosenescence, with cell-mediated immunity decreasing and systemic inflammation increasing, making...

Technical Information

  • File Format: PDF
  • File Size: 146 KB
  • Pages: 20
  • Language: EN
  • Author: emacuser
  • Total Downloads: 187
  • Last Updated: 2 weeks ago

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