Ladda Ner Fulltext (pdf) Av Agonistic CD40 Therapy Induces Tertiary Lymphoid Structures But Impairs Responses To Checkpoint Bloc.pdf

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Preview of Ladda ner fulltext (pdf) av Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint bloc
🔗 Source: uu.diva-portal.org
📊 Size: 3.02 MB
👤 Author: Luuk Hooren
⬇️ Downloads: 181

Summary

Agonistic CD40 therapy induces tertiary lymphoid structures in glioma models, but impairs responses to checkpoint blockade, associated with hypofunctional T cells and suppressive CD11b+ B cells. Tertiary lymphoid structures are present in human glioma and correlate with increased T cell infiltration, suggesting a role in regulating immune responses in glioma patients.

Description

Agonistic CD40 therapy induces tertiary lymphoid structures in glioma models, but impairs responses to checkpoint blockade, associated with hypofunctional T...

Technical Information

  • File Format: PDF
  • File Size: 3.02 MB
  • Pages: 14
  • Language: EN
  • Author: Luuk Hooren
  • Total Downloads: 181
  • Last Updated: 3 days ago

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