Letöltés.pdf

211_004_04-Glutathione-and-Other-Disulfides.pdf
Preview of Letöltés
🔗 Source: jasco.hu
📊 Size: 1.34 MB
👤 Author: AL
⬇️ Downloads: 216

Summary

Antec Leyden B.V. and Antec (USA) present an application note on the analysis of glutathione (GSH) and other disulfides using a DECADE II electrochemical detector with Dual Cell Control (DCC). GSH is a tripeptide with important functions in detoxification, antioxidant activity, and amino acid transport. The DCC option allows control of two electrochemical cells for data acquisition. The analysis is performed using an ALEXYS 100 micro LC-EC system with a reactor cell for reduction of disulfides to thiols and a second cell for oxidative amperometric detection. The method allows quantification of thiols and disulfides, including GSH, GSSG, cysteine, and homocysteine. Experimental conditions are optimized, and results show good reproducibility with RSD values between 2-7% for peak heights and 2-6% for areas. The application note highlights the importance of GSH and other disulfides in pharmaceutical and biotech analysis.

Description

Antec Leyden B.V.

Technical Information

  • File Format: PDF
  • File Size: 1.34 MB
  • Pages: 4
  • Language: EN
  • Author: AL
  • Total Downloads: 216
  • Last Updated: 16 hours ago

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