Liposomal Drug Delivery.pdf

c5nr07734f1.pdf
Preview of Liposomal Drug Delivery
🔗 Source: rsc.org
📊 Size: 2.24 MB
👤 Author: h.gopi
⬇️ Downloads: 132

Summary

Researchers synthesized Fmoc-Asp(Coumarin)-OH and Fmoc-Dap(NBD)-OH fluorescent amino acids through von Pechmann condensation and SNAr reaction, respectively. They used these amino acids to study pH-sensitive coiled coils for enhanced liposomal drug delivery. The peptides' fluorescence and circular dichroism spectra were measured at various pH levels, showing pH-dependent changes in fluorescence intensity and circular dichroism signals. The results indicate potential applications in drug delivery systems.

Description

Researchers synthesized Fmoc-Asp(Coumarin)-OH and Fmoc-Dap(NBD)-OH fluorescent amino acids through von Pechmann condensation and SNAr reaction, respectively.

Technical Information

  • File Format: PDF
  • File Size: 2.24 MB
  • Pages: 24
  • Language: EN
  • Author: h.gopi
  • Total Downloads: 132
  • Last Updated: 1 week ago

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