Microfluidizer® Technology For Solvent-free Production Of Liposomes.pdf

app-note-solvent-free-liposome-production.pdf
Preview of Microfluidizer® Technology for solvent-free production of liposomes
🔗 Source: analytik.co.uk
📊 Size: 1.48 MB
👤 Author: Katie Farquhar
⬇️ Downloads: 267

Summary

Liposomes are versatile nanoparticles used for delivering Active Pharmaceutical Ingredients (API) and vaccines, but traditional methods of creating liposomes involve using solvents that must be removed, causing additional processing steps and health & safety considerations. A new process has been developed that can produce liposomes without the use of solvents, using Microfluidizer® technology, which achieves uniform and efficient vesicle size-reduction. This solvent-free process was demonstrated on two commonly made liposomal formulations, resulting in target particle size, low polydispersity index, and high encapsulation efficiency. The results match products that are already clinically approved, and the liposome particle size, PDI, and drug loading remain unchanged throughout manufacturing steps.

Description

Liposomes are versatile nanoparticles used for delivering Active Pharmaceutical Ingredients (API) and vaccines, but traditional methods of creating liposomes...

Technical Information

  • File Format: PDF
  • File Size: 1.48 MB
  • Pages: 3
  • Language: EN
  • Author: Katie Farquhar
  • Total Downloads: 267
  • Last Updated: 6 days ago

Document Overview

This PDF document about Microfluidizer® Technology for solvent-free production of liposomes provides comprehensive information and guidance. Whether you're a beginner or advanced user, this resource offers valuable insights into Microfluidizer® Technology for solvent-free production of liposomes.

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