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Perindopril Estimation.pdf

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Preview of Perindopril Estimation
🔗 Source: idosi.org
📊 Size: 210 KB
📄 Pages: 7 pages
⬇️ Downloads: 129

Summary

A UV-spectrophotometric method using Indigo Carmine was developed for estimating Perindopril Erbumine in pharmaceutical formulations. The method involves forming a colored complex with Indigo Carmine, with a wavelength maximum at 387.2 nm. The concentration range was 5-40 µg/ml, with a linear regression of 0.9996. The limit of detection (LOD) and limit of quantitation (LOQ) were 0.32 µg/ml and 0.49 µg/ml, respectively. The method was validated statistically and by recovery studies, showing no interference from common additives. Two methods were developed: Method A (Zero Order Spectroscopic Method) and Method B (Area Under Curve method). The results indicate the suitability of this method for routine quality control analysis of Perindopril Erbumine in formulations.

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Description

A UV-spectrophotometric method using Indigo Carmine was developed for estimating Perindopril Erbumine in pharmaceutical formulations.

Technical Information

  • File Format: PDF
  • File Size: 210 KB
  • Pages: 7
  • Language: EN
  • Total Downloads: 129
  • Last Updated: 6 days ago

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