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Supplementary Information.pdf

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👤 Author: Clemens
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Summary

Supplementary Figure 1 shows acute induced NB-GMC fusion in Drosophila larval brains, where neural stem cells divide asymmetrically, generating a Prospero-positive ganglion mother cell (GMC) while self-renewing the neuroblast. Figure 1a is a schematic representation, and figures 1b-1e show experimental outlines and representative examples of metaphase and anaphase neuroblasts with GMC nuclei moving into the neuroblast, resulting in hybrid cells. Supplementary Figure 2 demonstrates that non-mitotic GMCs adjust their cell cycle to the parental NB after induced fusion, using Fly-FUCCI to determine cell cycle stages, with figures 2a-2g showing representative examples and quantifications of cell cycle stages in neuroblast lineages and GMCs.

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Supplementary Figure 1 shows acute induced NB-GMC fusion in Drosophila larval brains, where neural stem cells divide asymmetrically, generating a...

Technical Information

  • File Format: PDF
  • File Size: 13.28 MB
  • Pages: 14
  • Language: EN
  • Author: Clemens
  • Total Downloads: 433
  • Last Updated: 1 week ago

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