Télécharger Le Fichier.pdf

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Preview of Télécharger le fichier
🔗 Source: amu.hal.science
📊 Size: 1.44 MB
👤 Author: Christine T. Dinh, Stefania Goncalves, Esperanza Bas, Thomas R. van de Water, Azel Zine
⬇️ Downloads: 101

Summary

Loss of auditory sensory hair cells is the most common cause of hearing loss, and this review addresses the signaling pathways involved in their programmed and necrotic cell death in response to ototoxic and traumatic stressor events. The roles of inflammatory processes, oxidative stress, mitochondrial damage, cell death receptors, and members of the mitogen-activated protein kinase (MAPK) signal pathway are explored. The molecular interaction of these signal pathways that initiates the loss of auditory hair cells following acoustic trauma is covered, and possible therapeutic interventions to protect these sensory cells from loss via apoptotic or non-apoptotic cell death are discussed.

Description

Loss of auditory sensory hair cells is the most common cause of hearing loss, and this review addresses the signaling pathways involved in their programmed and...

Technical Information

  • File Format: PDF
  • File Size: 1.44 MB
  • Pages: 16
  • Language: EN
  • Author: Christine T. Dinh, Stefania Goncalves, Esperanza Bas, Thomas R. van de Water, Azel Zine
  • Total Downloads: 101
  • Last Updated: 3 weeks ago

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