Laryngeal Cancer.pdf

Malignant_lesions_of_the_Larynx_RPenn_11-12-08_0.pdf
Preview of Laryngeal Cancer
🔗 Source: uclahealth.org
📊 Size: 903 KB
👤 Author: abie mendelsohn
⬇️ Downloads: 147

Summary

Laryngeal cancer has 10,000 new cases and 3,900 deaths annually in the US, with a male-to-female ratio decreasing from 15:1 to 5:1 since 1950. Risk factors include tobacco, with a 13-fold increased risk, and alcohol, with a 34-fold increased risk for consuming over 1.5 liters of wine per day. Survival rates have decreased, particularly for advanced-stage glottic cancer and early-stage supraglottic cancers, possibly due to changes in management patterns. Genetic risk factors include aneuploidy, tumor suppressor gene inactivation, and proto-oncogene activation, while other risk factors include HPV, GERD, and mutagen-induced chromosome breaks.

Description

Laryngeal cancer has 10,000 new cases and 3,900 deaths annually in the US, with a male-to-female ratio decreasing from 15:1 to 5:1 since 1950.

Technical Information

  • File Format: PDF
  • File Size: 903 KB
  • Pages: 42
  • Language: EN
  • Author: abie mendelsohn
  • Total Downloads: 147
  • Last Updated: 1 month ago

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